| Conferencia este | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | Charlotte FC | 15 | 37 | 30:12 | 18 | 12 | 1 | 2 |
| 2. | Philadelphia Union | 15 | 34 | 34:15 | 19 | 10 | 4 | 1 |
| 3. | Nashville SC | 15 | 33 | 31:11 | 20 | 10 | 3 | 2 |
| 4. | New York Red Bulls | 15 | 33 | 34:19 | 15 | 10 | 3 | 2 |
| 5. | Columbus Crew | 15 | 28 | 25:18 | 7 | 8 | 4 | 3 |
| 6. | New York City FC | 13 | 27 | 22:13 | 9 | 9 | 0 | 4 |
| 7. | Cincinnati FC | 15 | 26 | 23:18 | 5 | 8 | 2 | 5 |
| 8. | Orlando City | 14 | 24 | 31:21 | 10 | 7 | 3 | 4 |
| 9. | Inter Miami CF | 12 | 24 | 27:17 | 10 | 7 | 3 | 2 |
| 10. | Chicago Fire | 15 | 20 | 21:23 | -2 | 5 | 5 | 5 |
| 11. | Atlanta United FC | 15 | 18 | 27:27 | 0 | 4 | 6 | 5 |
| 12. | D.C. United | 15 | 13 | 13:24 | -11 | 2 | 7 | 6 |
| 13. | Toronto FC | 15 | 12 | 12:16 | -4 | 2 | 6 | 7 |
| 14. | New England Revolution | 15 | 12 | 16:23 | -7 | 3 | 3 | 9 |
| 15. | CF Montreal | 15 | 11 | 13:30 | -17 | 2 | 5 | 8 |
| Conferencia oeste | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | Vancouver Whitecaps | 14 | 30 | 36:16 | 20 | 9 | 3 | 2 |
| 2. | Seattle Sounders | 14 | 29 | 34:18 | 16 | 8 | 5 | 1 |
| 3. | Los Angeles FC | 14 | 26 | 24:12 | 12 | 8 | 2 | 4 |
| 4. | San Diego FC | 16 | 26 | 25:16 | 9 | 7 | 5 | 4 |
| 5. | Colorado Rapids | 15 | 26 | 22:18 | 4 | 8 | 2 | 5 |
| 6. | Portland Timbers | 15 | 26 | 23:20 | 3 | 7 | 5 | 3 |
| 7. | Minnesota United FC | 15 | 25 | 26:17 | 9 | 7 | 4 | 4 |
| 8. | Real Salt Lake | 14 | 22 | 18:16 | 2 | 7 | 1 | 6 |
| 9. | Austin FC | 14 | 22 | 14:12 | 2 | 5 | 7 | 2 |
| 10. | San Jose Earthquakes | 15 | 18 | 34:28 | 6 | 4 | 6 | 5 |
| 11. | St. Louis City SC | 15 | 17 | 21:23 | -2 | 4 | 5 | 6 |
| 12. | Sporting Kansas City | 15 | 16 | 25:30 | -5 | 4 | 4 | 7 |
| 13. | FC Dallas | 15 | 15 | 21:23 | -2 | 4 | 3 | 8 |
| 14. | Houston Dynamo | 15 | 15 | 17:26 | -9 | 4 | 3 | 8 |
| 15. | Los Angeles Galaxy | 13 | 14 | 17:22 | -5 | 4 | 2 | 7 |