| Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | ||
|---|---|---|---|---|---|---|---|---|
| 1. | Cincinnati FC | 24 | 48 | 39:31 | 8 | 15 | 3 | 6 |
| 2. | Nashville SC | 24 | 47 | 42:25 | 17 | 14 | 5 | 5 |
| 3. | Philadelphia Union | 24 | 47 | 40:23 | 17 | 14 | 5 | 5 |
| 4. | Columbus Crew | 24 | 44 | 40:33 | 7 | 12 | 8 | 4 |
| 5. | San Diego FC | 24 | 43 | 47:32 | 15 | 13 | 4 | 7 |
| 6. | Vancouver Whitecaps | 23 | 42 | 39:26 | 13 | 12 | 6 | 5 |
| 7. | Inter Miami CF | 21 | 41 | 49:34 | 15 | 12 | 5 | 4 |
| 8. | Minnesota United FC | 24 | 41 | 40:27 | 13 | 11 | 8 | 5 |
| 9. | Orlando City | 24 | 38 | 43:32 | 11 | 10 | 8 | 6 |
| 10. | Seattle Sounders | 23 | 37 | 37:33 | 4 | 10 | 7 | 6 |
| 11. | Los Angeles FC | 21 | 36 | 39:27 | 12 | 10 | 6 | 5 |
| 12. | New York City FC | 23 | 35 | 30:26 | 4 | 10 | 5 | 8 |
| 13. | Charlotte FC | 24 | 35 | 41:39 | 2 | 11 | 2 | 11 |
| 14. | Portland Timbers | 23 | 34 | 32:32 | 0 | 9 | 7 | 7 |
| 15. | New York Red Bulls | 24 | 33 | 39:35 | 4 | 9 | 6 | 9 |
| 16. | Chicago Fire | 23 | 32 | 44:40 | 4 | 9 | 5 | 9 |
| 17. | Colorado Rapids | 24 | 30 | 30:36 | -6 | 8 | 6 | 10 |
| 18. | Austin FC | 22 | 30 | 17:24 | -7 | 8 | 6 | 8 |
| 19. | San Jose Earthquakes | 24 | 29 | 46:42 | 4 | 7 | 8 | 9 |
| 20. | Real Salt Lake | 23 | 28 | 24:29 | -5 | 8 | 4 | 11 |
| 21. | Houston Dynamo | 24 | 27 | 30:39 | -9 | 7 | 6 | 11 |
| 22. | New England Revolution | 23 | 25 | 30:32 | -2 | 6 | 7 | 10 |
| 23. | FC Dallas | 23 | 25 | 32:41 | -9 | 6 | 7 | 10 |
| 24. | Sporting Kansas City | 23 | 24 | 36:42 | -6 | 6 | 6 | 11 |
| 25. | Toronto FC | 23 | 21 | 25:30 | -5 | 5 | 6 | 12 |
| 26. | Atlanta United FC | 23 | 20 | 27:43 | -16 | 4 | 8 | 11 |
| 27. | D.C. United | 24 | 19 | 20:45 | -25 | 4 | 7 | 13 |
| 28. | St. Louis City SC | 23 | 18 | 23:38 | -15 | 4 | 6 | 13 |
| 29. | Los Angeles Galaxy | 24 | 16 | 28:48 | -20 | 3 | 7 | 14 |
| 30. | CF Montreal | 24 | 15 | 20:45 | -25 | 3 | 6 | 15 |