| Conferencia este | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | Cincinnati FC | 8 | 19 | 15:10 | 5 | 6 | 1 | 1 |
| 2. | Inter Miami CF | 8 | 17 | 16:12 | 4 | 5 | 2 | 1 |
| 3. | Philadelphia Union | 8 | 14 | 15:9 | 6 | 3 | 5 | 0 |
| 4. | Columbus Crew | 7 | 12 | 11:7 | 4 | 3 | 3 | 1 |
| 5. | New York Red Bulls | 9 | 12 | 14:17 | -3 | 3 | 3 | 3 |
| 6. | New York City FC | 7 | 10 | 7:8 | -1 | 3 | 1 | 3 |
| 7. | Orlando City | 6 | 10 | 9:13 | -4 | 3 | 1 | 2 |
| 8. | CF Montreal | 9 | 8 | 10:22 | -12 | 2 | 2 | 5 |
| 9. | D.C. United | 7 | 7 | 8:10 | -2 | 1 | 4 | 2 |
| 10. | Toronto FC | 7 | 7 | 6:12 | -6 | 2 | 1 | 4 |
| 11. | Charlotte FC | 6 | 4 | 4:7 | -3 | 1 | 1 | 4 |
| 12. | Chicago Fire | 7 | 4 | 6:12 | -6 | 0 | 4 | 3 |
| 13. | Atlanta United FC | 6 | 3 | 2:6 | -4 | 0 | 3 | 3 |
| 14. | New England Revolution | 6 | 3 | 5:14 | -9 | 1 | 0 | 5 |
| 15. | Nashville SC | 5 | 2 | 2:10 | -8 | 0 | 2 | 3 |
| Conferencia oeste | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | Real Salt Lake | 8 | 13 | 15:11 | 4 | 3 | 4 | 1 |
| 2. | Minnesota United FC | 6 | 13 | 13:9 | 4 | 4 | 1 | 1 |
| 3. | Los Angeles Galaxy | 9 | 13 | 14:12 | 2 | 3 | 4 | 2 |
| 4. | Vancouver Whitecaps | 7 | 11 | 9:7 | 2 | 3 | 2 | 2 |
| 5. | Colorado Rapids | 8 | 11 | 15:15 | 0 | 3 | 2 | 3 |
| 6. | Seattle Sounders | 9 | 10 | 11:14 | -3 | 3 | 1 | 5 |
| 7. | Houston Dynamo | 7 | 9 | 7:9 | -2 | 3 | 0 | 4 |
| 8. | Los Angeles FC | 7 | 7 | 8:13 | -5 | 2 | 1 | 4 |
| 9. | Austin FC | 7 | 6 | 3:6 | -3 | 1 | 3 | 3 |
| 10. | Sporting Kansas City | 7 | 5 | 8:10 | -2 | 1 | 2 | 4 |
| 11. | Portland Timbers | 8 | 5 | 12:17 | -5 | 1 | 2 | 5 |
| 12. | St. Louis City SC | 6 | 4 | 10:14 | -4 | 0 | 4 | 2 |
| 13. | San Jose Earthquakes | 8 | 4 | 15:21 | -6 | 1 | 1 | 6 |
| 14. | FC Dallas | 6 | 2 | 5:10 | -5 | 0 | 2 | 4 |