| Conferencia este | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | CF Montreal | 17 | 35 | 33:29 | 4 | 11 | 2 | 4 |
| 2. | New York Red Bulls | 17 | 30 | 24:19 | 5 | 9 | 3 | 5 |
| 3. | Philadelphia Union | 17 | 26 | 23:17 | 6 | 7 | 5 | 5 |
| 4. | Cincinnati FC | 17 | 25 | 27:29 | -2 | 6 | 7 | 4 |
| 5. | New York City FC | 17 | 21 | 20:22 | -2 | 6 | 3 | 8 |
| 6. | Orlando City | 17 | 21 | 18:25 | -7 | 5 | 6 | 6 |
| 7. | Columbus Crew | 17 | 19 | 24:26 | -2 | 3 | 10 | 4 |
| 8. | Chicago Fire | 17 | 16 | 21:31 | -10 | 4 | 4 | 9 |
| 9. | New England Revolution | 17 | 15 | 25:34 | -9 | 3 | 6 | 8 |
| 10. | Inter Miami CF | 17 | 15 | 13:28 | -15 | 4 | 3 | 10 |
| 11. | Atlanta United FC | 17 | 11 | 17:30 | -13 | 2 | 5 | 10 |
| 12. | Charlotte FC | 17 | 11 | 16:36 | -20 | 3 | 2 | 12 |
| 13. | D.C. United | 17 | 11 | 14:37 | -23 | 3 | 2 | 12 |
| 14. | Toronto FC | 17 | 10 | 19:37 | -18 | 2 | 4 | 11 |
| Conferencia oeste | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | Los Angeles FC | 17 | 26 | 27:23 | 4 | 8 | 2 | 7 |
| 2. | Nashville SC | 18 | 26 | 22:21 | 1 | 7 | 5 | 6 |
| 3. | Austin FC | 18 | 26 | 23:29 | -6 | 8 | 2 | 8 |
| 4. | Los Angeles Galaxy | 18 | 22 | 25:29 | -4 | 6 | 4 | 8 |
| 5. | FC Dallas | 18 | 19 | 21:24 | -3 | 4 | 7 | 7 |
| 6. | Minnesota United FC | 18 | 19 | 26:37 | -11 | 6 | 1 | 11 |
| 7. | Portland Timbers | 17 | 16 | 25:34 | -9 | 3 | 7 | 7 |
| 8. | Real Salt Lake | 18 | 15 | 19:35 | -16 | 3 | 6 | 9 |
| 9. | Houston Dynamo | 17 | 13 | 19:34 | -15 | 4 | 1 | 12 |
| 10. | Seattle Sounders | 17 | 11 | 18:27 | -9 | 3 | 2 | 12 |
| 11. | Sporting Kansas City | 17 | 11 | 17:37 | -20 | 2 | 5 | 10 |
| 12. | Vancouver Whitecaps | 17 | 10 | 15:37 | -22 | 2 | 4 | 11 |
| 13. | San Jose Earthquakes | 17 | 8 | 21:42 | -21 | 1 | 5 | 11 |
| 14. | Colorado Rapids | 17 | 8 | 17:42 | -25 | 1 | 5 | 11 |