| Conferencia este | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | Inter Miami CF | 17 | 33 | 34:28 | 6 | 10 | 3 | 4 |
| 2. | Nashville SC | 17 | 30 | 23:11 | 12 | 8 | 6 | 3 |
| 3. | Chicago Fire | 17 | 26 | 31:29 | 2 | 7 | 5 | 5 |
| 4. | New England Revolution | 17 | 23 | 24:27 | -3 | 7 | 2 | 8 |
| 5. | Philadelphia Union | 17 | 21 | 34:33 | 1 | 6 | 3 | 8 |
| 6. | New York City FC | 17 | 21 | 19:21 | -2 | 5 | 6 | 6 |
| 7. | Charlotte FC | 17 | 20 | 29:35 | -6 | 5 | 5 | 7 |
| 8. | Columbus Crew | 17 | 18 | 30:33 | -3 | 5 | 3 | 9 |
| 9. | New York Red Bulls | 17 | 18 | 21:33 | -12 | 5 | 3 | 9 |
| 10. | Atlanta United FC | 17 | 16 | 17:27 | -10 | 4 | 4 | 9 |
| 11. | Cincinnati FC | 17 | 16 | 28:43 | -15 | 3 | 7 | 7 |
| 12. | D.C. United | 17 | 13 | 19:32 | -13 | 2 | 7 | 8 |
| 13. | Orlando City | 17 | 13 | 30:56 | -26 | 3 | 4 | 10 |
| 14. | Toronto FC | 17 | 12 | 16:34 | -18 | 3 | 3 | 11 |
| 15. | CF Montreal | 17 | 9 | 18:44 | -26 | 2 | 3 | 12 |
| Conferencia oeste | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | Vancouver Whitecaps | 17 | 29 | 30:18 | 12 | 8 | 5 | 4 |
| 2. | FC Dallas | 17 | 26 | 30:28 | 2 | 7 | 5 | 5 |
| 3. | San Jose Earthquakes | 17 | 26 | 27:25 | 2 | 7 | 5 | 5 |
| 4. | St. Louis City SC | 17 | 23 | 23:25 | -2 | 6 | 5 | 6 |
| 5. | Houston Dynamo | 17 | 22 | 24:28 | -4 | 6 | 4 | 7 |
| 6. | Minnesota United FC | 17 | 22 | 31:36 | -5 | 6 | 4 | 7 |
| 7. | Seattle Sounders | 17 | 18 | 18:23 | -5 | 4 | 6 | 7 |
| 8. | Los Angeles Galaxy | 17 | 17 | 24:36 | -12 | 4 | 5 | 8 |
| 9. | Los Angeles FC | 17 | 16 | 20:22 | -2 | 3 | 7 | 7 |
| 10. | Austin FC | 17 | 16 | 20:40 | -20 | 4 | 4 | 9 |
| 11. | Portland Timbers | 17 | 15 | 25:33 | -8 | 4 | 3 | 10 |
| 12. | San Diego FC | 17 | 15 | 20:33 | -13 | 3 | 6 | 8 |
| 13. | Real Salt Lake | 17 | 12 | 20:30 | -10 | 3 | 3 | 11 |
| 14. | Sporting Kansas City | 17 | 12 | 16:46 | -30 | 4 | 0 | 13 |
| 15. | Colorado Rapids | 17 | 10 | 16:31 | -15 | 2 | 4 | 11 |