| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 4/12/22 1:00 | Detroit Red Wings | Vegas Golden Knights | 1:4 |
| 4/12/22 1:00 | Philadelphia Flyers | New Jersey Devils | 2:3 |
| 4/12/22 1:00 | Edmonton Oilers | Montréal Canadiens | 5:3 |
| 4/12/22 1:00 | Ottawa Senators | San Jose Sharks | 5:2 |
| 4/12/22 1:00 | Boston Bruins | Colorado Avalanche | 5:1 |
| 4/12/22 1:00 | Tampa Bay Lightning | Toronto Maple Leafs | 4:3OT |
| 4/12/22 1:00 | Pittsburgh Penguins | St. Louis Blues | 6:2 |
| 4/12/22 1:30 | New York Rangers | Chicago Blackhawks | 2:5 |
| 4/12/22 4:00 | Calgary Flames | Washington Capitals | 5:2 |
| 4/12/22 4:00 | Vancouver Canucks | Arizona Coyotes | 3:2OT |
| 4/12/22 4:00 | Seattle Kraken | Florida Panthers | 1:5 |
| 4/12/22 4:30 | Los Angeles Kings | Carolina Hurricanes | 2:4 |
| 4/12/22 21:00 | Dallas Stars | Minnesota Wild | 5:6t.t.p. |
| 4/12/22 21:00 | Winnipeg Jets | Anaheim Ducks | 5:2 |