| Conferencia este | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | Nashville SC | 25 | 54 | 50:21 | 29 | 16 | 6 | 3 |
| 2. | Inter Miami CF | 25 | 45 | 61:46 | 15 | 12 | 9 | 4 |
| 3. | Charlotte FC | 25 | 40 | 45:36 | 9 | 11 | 7 | 7 |
| 4. | New England Revolution | 24 | 40 | 39:30 | 9 | 12 | 4 | 8 |
| 5. | Chicago Fire | 23 | 39 | 44:33 | 11 | 11 | 6 | 6 |
| 6. | Orlando City | 25 | 34 | 44:56 | -12 | 10 | 4 | 11 |
| 7. | New York City FC | 25 | 32 | 39:33 | 6 | 8 | 8 | 9 |
| 8. | Cincinnati FC | 24 | 32 | 52:59 | -7 | 8 | 8 | 8 |
| 9. | Philadelphia Union | 24 | 30 | 41:39 | 2 | 8 | 6 | 10 |
| 10. | New York Red Bulls | 25 | 30 | 33:48 | -15 | 8 | 6 | 11 |
| 11. | D.C. United | 24 | 29 | 30:37 | -7 | 6 | 11 | 7 |
| 12. | Toronto FC | 25 | 29 | 38:46 | -8 | 6 | 11 | 8 |
| 13. | Columbus Crew | 25 | 23 | 35:42 | -7 | 6 | 5 | 14 |
| 14. | Atlanta United FC | 25 | 23 | 29:43 | -14 | 6 | 5 | 14 |
| 15. | CF Montreal | 25 | 21 | 31:51 | -20 | 5 | 6 | 14 |
| Conferencia oeste | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | Vancouver Whitecaps | 23 | 46 | 52:21 | 31 | 14 | 4 | 5 |
| 2. | FC Dallas | 25 | 43 | 49:42 | 7 | 12 | 7 | 6 |
| 3. | Houston Dynamo | 25 | 43 | 32:28 | 4 | 13 | 4 | 8 |
| 4. | San Jose Earthquakes | 25 | 41 | 44:36 | 8 | 12 | 5 | 8 |
| 5. | St. Louis City SC | 25 | 41 | 42:35 | 7 | 11 | 8 | 6 |
| 6. | Los Angeles FC | 26 | 40 | 41:27 | 14 | 11 | 7 | 8 |
| 7. | Colorado Rapids | 25 | 35 | 33:32 | 1 | 11 | 2 | 12 |
| 8. | Portland Timbers | 25 | 32 | 47:47 | 0 | 9 | 5 | 11 |
| 9. | San Diego FC | 24 | 30 | 42:37 | 5 | 8 | 6 | 10 |
| 10. | Los Angeles Galaxy | 26 | 30 | 31:40 | -9 | 7 | 9 | 10 |
| 11. | Real Salt Lake | 24 | 29 | 37:39 | -2 | 8 | 5 | 11 |
| 12. | Minnesota United FC | 25 | 29 | 37:43 | -6 | 7 | 8 | 10 |
| 13. | Seattle Sounders | 23 | 28 | 25:30 | -5 | 7 | 7 | 9 |
| 14. | Austin FC | 24 | 26 | 30:43 | -13 | 6 | 8 | 10 |
| 15. | Sporting Kansas City | 24 | 18 | 26:59 | -33 | 5 | 3 | 16 |