| Conferencia este | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | Inter Miami CF | 13 | 27 | 28:22 | 6 | 8 | 3 | 2 |
| 2. | Nashville SC | 13 | 20 | 14:9 | 5 | 5 | 5 | 3 |
| 3. | Chicago Fire | 12 | 17 | 23:21 | 2 | 4 | 5 | 3 |
| 4. | New York City FC | 12 | 16 | 13:13 | 0 | 4 | 4 | 4 |
| 5. | Charlotte FC | 12 | 15 | 19:23 | -4 | 4 | 3 | 5 |
| 6. | New York Red Bulls | 13 | 15 | 15:25 | -10 | 4 | 3 | 6 |
| 7. | New England Revolution | 12 | 14 | 17:19 | -2 | 4 | 2 | 6 |
| 8. | D.C. United | 11 | 12 | 13:14 | -1 | 2 | 6 | 3 |
| 9. | Philadelphia Union | 12 | 11 | 22:28 | -6 | 3 | 2 | 7 |
| 10. | Orlando City | 12 | 11 | 21:39 | -18 | 3 | 2 | 7 |
| 11. | Atlanta United FC | 13 | 10 | 12:22 | -10 | 2 | 4 | 7 |
| 12. | Toronto FC | 11 | 9 | 9:18 | -9 | 2 | 3 | 6 |
| 13. | Cincinnati FC | 12 | 8 | 18:35 | -17 | 1 | 5 | 6 |
| 14. | CF Montreal | 13 | 7 | 15:36 | -21 | 2 | 1 | 10 |
| 15. | Columbus Crew | 12 | 6 | 18:27 | -9 | 1 | 3 | 8 |
| Conferencia oeste | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | San Jose Earthquakes | 13 | 24 | 24:17 | 7 | 7 | 3 | 3 |
| 2. | FC Dallas | 14 | 24 | 25:22 | 3 | 7 | 3 | 4 |
| 3. | Vancouver Whitecaps | 10 | 18 | 21:12 | 9 | 5 | 3 | 2 |
| 4. | St. Louis City SC | 13 | 17 | 17:19 | -2 | 4 | 5 | 4 |
| 5. | Houston Dynamo | 13 | 17 | 17:20 | -3 | 5 | 2 | 6 |
| 6. | Minnesota United FC | 13 | 17 | 25:30 | -5 | 5 | 2 | 6 |
| 7. | Los Angeles FC | 13 | 14 | 16:16 | 0 | 3 | 5 | 5 |
| 8. | Seattle Sounders | 12 | 13 | 9:12 | -3 | 3 | 4 | 5 |
| 9. | Los Angeles Galaxy | 13 | 13 | 16:24 | -8 | 3 | 4 | 6 |
| 10. | San Diego FC | 11 | 9 | 10:18 | -8 | 2 | 3 | 6 |
| 11. | Austin FC | 12 | 9 | 14:31 | -17 | 2 | 3 | 7 |
| 12. | Portland Timbers | 12 | 8 | 16:23 | -7 | 2 | 2 | 8 |
| 13. | Colorado Rapids | 13 | 8 | 11:23 | -12 | 2 | 2 | 9 |
| 14. | Real Salt Lake | 12 | 6 | 13:22 | -9 | 1 | 3 | 8 |
| 15. | Sporting Kansas City | 12 | 6 | 11:37 | -26 | 2 | 0 | 10 |