| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 4/10/22 20:45 | Luton Town | Huddersfield Town | 3:3 |
| 4/10/22 20:45 | Bristol City | Coventry City | 0:0 |
| 4/10/22 20:45 | Sheffield United | Queens Park Rangers | 0:1 |
| 4/10/22 20:45 | AFC Sunderland | FC Blackpool | 0:0 |
| 4/10/22 21:00 | Cardiff City | Blackburn Rovers | 1:0 |
| 4/10/22 21:00 | FC Reading | Norwich City | 1:1 |
| 5/10/22 20:45 | Hull City A.F.C. | Wigan Athletic | 2:1 |
| 5/10/22 20:45 | Rotherham United | FC Millwall | 1:1 |
| 5/10/22 20:45 | FC Middlesbrough | Birmingham City | 1:0 |
| 5/10/22 20:45 | FC Burnley | FC Stoke City | 1:1 |
| 5/10/22 20:45 | FC Watford | Swansea City | 1:2 |
| 5/10/22 21:00 | Preston North End | West Bromwich Albion | 1:0 |