| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 9/12/25 16:30 | Qairat Almaty | Olympiacos Piräus | -:- |
| 9/12/25 18:45 | FC Bayern de Múnich | Sporting de Portugal | -:- |
| 9/12/25 21:00 | AS Monaco | Galatasaray Estanbul | -:- |
| 9/12/25 21:00 | F. C. Barcelona | Eintracht Frankfurt | -:- |
| 9/12/25 21:00 | PSV Eindhoven | Club Atlético de Madrid | -:- |
| 9/12/25 21:00 | Atalanta Bergamo | FC Chelsea | -:- |
| 9/12/25 21:00 | Tottenham | Slavia Praga | -:- |
| 9/12/25 21:00 | Royale Union Saint-Gilloise | Olympique Marseille | -:- |
| 9/12/25 21:00 | Inter de Milán | Liverpool FC | -:- |
| 10/12/25 18:45 | Villarreal C. F. | FC Copenhague | -:- |
| 10/12/25 18:45 | Qarabag | Ajax Amsterdam | -:- |
| 10/12/25 21:00 | Athletic Club | Paris St. Germain | -:- |
| 10/12/25 21:00 | Bayer Leverkusen | Newcastle United | -:- |
| 10/12/25 21:00 | Borussia Dortmund | FK Bodö/Glimt | -:- |
| 10/12/25 21:00 | Club Brujas | Arsenal FC | -:- |
| 10/12/25 21:00 | Juventus de Turin | Pafos FC | -:- |
| 10/12/25 21:00 | Real Madrid C. F. | Manchester City | -:- |
| 10/12/25 21:00 | Benfica Lisboa | Nápoles | -:- |