| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 21/10/25 18:45 | F. C. Barcelona | Olympiacos Piräus | -:- |
| 21/10/25 18:45 | Qairat Almaty | Pafos FC | -:- |
| 21/10/25 21:00 | PSV Eindhoven | Nápoles | -:- |
| 21/10/25 21:00 | Villarreal C. F. | Manchester City | -:- |
| 21/10/25 21:00 | FC Copenhague | Borussia Dortmund | -:- |
| 21/10/25 21:00 | Royale Union Saint-Gilloise | Inter de Milán | -:- |
| 21/10/25 21:00 | Arsenal FC | Club Atlético de Madrid | -:- |
| 21/10/25 21:00 | Newcastle United | Benfica Lisboa | -:- |
| 21/10/25 21:00 | Bayer Leverkusen | Paris St. Germain | -:- |
| 22/10/25 18:45 | Galatasaray Estanbul | FK Bodö/Glimt | -:- |
| 22/10/25 18:45 | Athletic Club | Qarabag | -:- |
| 22/10/25 21:00 | Real Madrid C. F. | Juventus de Turin | -:- |
| 22/10/25 21:00 | FC Bayern de Múnich | Club Brujas | -:- |
| 22/10/25 21:00 | FC Chelsea | Ajax Amsterdam | -:- |
| 22/10/25 21:00 | Eintracht Frankfurt | Liverpool FC | -:- |
| 22/10/25 21:00 | Atalanta Bergamo | Slavia Praga | -:- |
| 22/10/25 21:00 | Sporting de Portugal | Olympique Marseille | -:- |
| 22/10/25 21:00 | AS Monaco | Tottenham | -:- |