| Conferencia este | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | Nashville SC | 11 | 24 | 23:8 | 15 | 7 | 3 | 1 |
| 2. | New England Revolution | 11 | 22 | 20:13 | 7 | 7 | 1 | 3 |
| 3. | Inter Miami CF | 12 | 22 | 26:21 | 5 | 6 | 4 | 2 |
| 4. | Chicago Fire | 11 | 17 | 20:14 | 6 | 5 | 2 | 4 |
| 5. | D.C. United | 12 | 16 | 15:17 | -2 | 4 | 4 | 4 |
| 6. | Cincinnati FC | 12 | 16 | 24:27 | -3 | 4 | 4 | 4 |
| 7. | New York City FC | 12 | 15 | 22:18 | 4 | 4 | 3 | 5 |
| 8. | Charlotte FC | 12 | 15 | 20:21 | -1 | 4 | 3 | 5 |
| 9. | New York Red Bulls | 12 | 15 | 19:28 | -9 | 4 | 3 | 5 |
| 10. | Toronto FC | 12 | 14 | 20:24 | -4 | 3 | 5 | 4 |
| 11. | Columbus Crew | 12 | 12 | 16:19 | -3 | 3 | 3 | 6 |
| 12. | CF Montreal | 11 | 12 | 16:23 | -7 | 4 | 0 | 7 |
| 13. | Atlanta United FC | 12 | 10 | 13:20 | -7 | 3 | 1 | 8 |
| 14. | Orlando City | 12 | 10 | 16:34 | -18 | 3 | 1 | 8 |
| 15. | Philadelphia Union | 12 | 6 | 10:19 | -9 | 1 | 3 | 8 |
| Conferencia oeste | Par. | Pts | Goles | Dif | P.G. | P.E. | P.P. | |
|---|---|---|---|---|---|---|---|---|
| 1. | San Jose Earthquakes | 12 | 29 | 27:8 | 19 | 9 | 2 | 1 |
| 2. | Vancouver Whitecaps | 11 | 26 | 27:7 | 20 | 8 | 2 | 1 |
| 3. | Los Angeles FC | 12 | 21 | 20:12 | 8 | 6 | 3 | 3 |
| 4. | Seattle Sounders | 10 | 21 | 14:6 | 8 | 6 | 3 | 1 |
| 5. | Minnesota United FC | 12 | 21 | 16:18 | -2 | 6 | 3 | 3 |
| 6. | FC Dallas | 12 | 19 | 23:16 | 7 | 5 | 4 | 3 |
| 7. | Real Salt Lake | 11 | 19 | 20:17 | 3 | 6 | 1 | 4 |
| 8. | Houston Dynamo | 11 | 18 | 17:19 | -2 | 6 | 0 | 5 |
| 9. | Los Angeles Galaxy | 12 | 16 | 18:18 | 0 | 4 | 4 | 4 |
| 10. | Austin FC | 12 | 14 | 18:21 | -3 | 3 | 5 | 4 |
| 11. | Colorado Rapids | 12 | 13 | 22:20 | 2 | 4 | 1 | 7 |
| 12. | San Diego FC | 12 | 13 | 20:20 | 0 | 3 | 4 | 5 |
| 13. | Portland Timbers | 11 | 13 | 19:21 | -2 | 4 | 1 | 6 |
| 14. | St. Louis City SC | 11 | 9 | 10:18 | -8 | 2 | 3 | 6 |
| 15. | Sporting Kansas City | 11 | 5 | 8:32 | -24 | 1 | 2 | 8 |