| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 27/09/25 15:00 | US Avellino | Virtus Entella | -:- |
| 27/09/25 15:00 | SSC Bari | UC Sampdoria | -:- |
| 27/09/25 15:00 | FC Empoli | Carrarese Calcio 1908 | -:- |
| 27/09/25 15:00 | Mantova 1911 | Frosinone Calcio | -:- |
| 27/09/25 15:00 | US Catanzaro 1929 | Juve Stabia | -:- |
| 27/09/25 15:00 | FC Cesena | Palermo FC | -:- |
| 27/09/25 15:00 | FC Südtirol | AC Reggiana 1919 | -:- |
| 27/09/25 15:00 | FC Venecia | Spezia Calcio | -:- |
| 27/09/25 15:00 | Modena FC | Pescara Calcio | -:- |
| 27/09/25 15:00 | AC Monza | Padova Calcio | -:- |
| 28/09/25 18:00 | Juventus de Turin | Atalanta Bergamo | -:- |
| 28/09/25 18:00 | Genua CFC | Lazio Roma | -:- |
| 28/09/25 18:00 | AC Milán | Nápoles | -:- |
| 28/09/25 18:00 | US Lecce | FC Bologna | -:- |
| 28/09/25 18:00 | Pisa Sporting Club | AC Fiorentina | -:- |
| 28/09/25 18:00 | Parma Calcio 1913 | Torino FC | -:- |
| 28/09/25 18:00 | Sassuolo Calcio | Udinese Calcio | -:- |
| 28/09/25 18:00 | AS Roma | Hellas Verona | -:- |
| 28/09/25 18:00 | Como Calcio | US Cremonese | -:- |
| 28/09/25 18:00 | Cagliari Calcio | Inter de Milán | -:- |