| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 20/09/25 15:00 | Spezia Calcio | Juve Stabia | -:- |
| 20/09/25 15:00 | FC Venecia | FC Cesena | -:- |
| 20/09/25 15:00 | Mantova 1911 | Modena FC | -:- |
| 20/09/25 15:00 | AC Monza | UC Sampdoria | -:- |
| 20/09/25 15:00 | Carrarese Calcio 1908 | US Avellino | -:- |
| 20/09/25 15:00 | Frosinone Calcio | FC Südtirol | -:- |
| 20/09/25 15:00 | Pescara Calcio | FC Empoli | -:- |
| 20/09/25 15:00 | AC Reggiana 1919 | US Catanzaro 1929 | -:- |
| 20/09/25 15:00 | Padova Calcio | Virtus Entella | -:- |
| 20/09/25 15:00 | Palermo FC | SSC Bari | -:- |
| 21/09/25 18:00 | AC Fiorentina | Como Calcio | -:- |
| 21/09/25 18:00 | US Cremonese | Parma Calcio 1913 | -:- |
| 21/09/25 18:00 | Lazio Roma | AS Roma | -:- |
| 21/09/25 18:00 | Inter de Milán | Sassuolo Calcio | -:- |
| 21/09/25 18:00 | Nápoles | Pisa Sporting Club | -:- |
| 21/09/25 18:00 | US Lecce | Cagliari Calcio | -:- |
| 21/09/25 18:00 | Udinese Calcio | AC Milán | -:- |
| 21/09/25 18:00 | Torino FC | Atalanta Bergamo | -:- |
| 21/09/25 18:00 | FC Bologna | Genua CFC | -:- |
| 21/09/25 18:00 | Hellas Verona | Juventus de Turin | -:- |