| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 29/08/25 18:30 | US Cremonese | Sassuolo Calcio | -:- |
| 29/08/25 20:30 | AC Reggiana 1919 | FC Empoli | -:- |
| 29/08/25 20:45 | US Lecce | AC Milán | -:- |
| 30/08/25 18:30 | Parma Calcio 1913 | Atalanta Bergamo | -:- |
| 30/08/25 18:30 | FC Bologna | Como Calcio | -:- |
| 30/08/25 19:00 | Juve Stabia | FC Venecia | -:- |
| 30/08/25 19:00 | Mantova 1911 | Pescara Calcio | -:- |
| 30/08/25 20:45 | Nápoles | Cagliari Calcio | -:- |
| 30/08/25 20:45 | Pisa Sporting Club | AS Roma | -:- |
| 30/08/25 21:00 | FC Cesena | Virtus Entella | -:- |
| 30/08/25 21:00 | Palermo FC | Frosinone Calcio | -:- |
| 30/08/25 21:00 | Spezia Calcio | US Catanzaro 1929 | -:- |
| 31/08/25 18:30 | Genua CFC | Juventus de Turin | -:- |
| 31/08/25 18:30 | Torino FC | AC Fiorentina | -:- |
| 31/08/25 19:00 | Carrarese Calcio 1908 | Padova Calcio | -:- |
| 31/08/25 19:00 | FC Südtirol | UC Sampdoria | -:- |
| 31/08/25 20:45 | Lazio Roma | Hellas Verona | -:- |
| 31/08/25 20:45 | Inter de Milán | Udinese Calcio | -:- |
| 31/08/25 21:00 | SSC Bari | AC Monza | -:- |
| 31/08/25 21:00 | Modena FC | US Avellino | -:- |